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产品目录

Hamartin/TSC1抗体图片
产品货号:
Z16981
中文名称:
Hamartin/TSC1抗体
英文名称:
Anti-Hamartin/TSC1 Antibody
产品规格:
50μl|100μl|150μl
发货周期:
1~3天
产品价格:
询价
抗体名称Anti-Hamartin/TSC1 Antibody
指标别名Hamartin;KIAA0243;LAM;TSC;TSC1;tuberous sclerosis 1;Tuberous sclerosis 1 protein
克隆性Polyclonal
检验物种human,mouse,rat
应用范围WB
基因名称TSC1
抗体来源Rabbit
抗体类型IgG
免疫原E.coli-derived human Hamartin recombinant protein (Position:D686-Y884).Human Hamartin shares 96% and 95% amino acid (aa) sequences identity with mouse and rat Hamartin,respectively.
实际分子量150KD
成分500μg/mL antibody with PBS,0.02% NaN3,1mg BSA and 50% glycerol.
纯化方式Immunogen affinity purified.
浓度500μg/mL
产品形态溶液
保存条件12 months from date of receipt,-20℃ as supplied.6 months 2 to 8℃ after reconstitution.Avoid repeated freezing and thawing.
背景资料Hamartin also known as tuberous sclerosis 1 is a protein that in humans is encoded by the TSC1 gene.It is mapped to 9q34.13.This peripheral membrane protein was implicated as a tumor suppressor.It forms a complex with TSC2 that regulates mTORC1 signaling and may be also involved in vesicular transport and docking.Hamartin and TSC2 have critical roles in neuronal polarity,and that a common pathway regulates polarization and growth in neurons and cell size in other tissues.Hamartin is a growth inhibitory protein whose biologic effect is probably dependent on its interaction with tuberin.It also can affect cell proliferation via deregulation of G1 phase.Loss or perturbation of Hamartin function leads to loss of adhesion to the cellular matrix and initiates the development of TSC hamartomas.
Uniprot IDQ92574
推荐配套试剂Biorab recommends Enhanced Chemiluminescent Kit with anti-Rabbit IgG (ZN1926) for Western blot,and HRP Conjugated anti-Rabbit IgG Super Vision Assay Kit (ZN1865) for IHC(P).*Blocking peptide可以联系我们购买。
基因名全称tuberous sclerosis 1
蛋白名全称Hamartin
推荐稀释比
Western blot(WB) 1:500~2000

相关搜索:Hamartin/TSC1抗体Hamartin抗体TSC1多抗Anti-Hamartin/TSC1 Antibody
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